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Major Breakthrough in Male Contraceptive

... Editorial Team

There have been a slew of developments in the world of birth control for both men and women. Male contraception has been the focus of lots of research and a solution has been on the cards for quite some time now. However,  a major announcement on this front has eluded us till now. The researchers, though, have been continuously working on finding one or several effective methods for quite some time now. Back in 2014, scientists successfully rendered three male baboons infertile for six months using an injectable polymer gel called Vasalgel. But in the world of hormonal contraception, it’s been awhile since we’ve heard about any new developments. 

Researchers at the University of Minnesota’s College of Pharmacy have revealed exciting new findings in at the American Chemical Society’s national meeting  in San Diego, California. The news is definitely very promising — and like many medical innovations, it was discovered by accident. Back in the ’80s, certain chemical compounds had been tested to treat skin conditions, but one side effect halted the study: The compound resulted in a vitamin A deficiency that then led to temporary sterility.

According to Forbes, “When they were rediscovered in the early 2000s, early tests with animals found they blocked sperm production, were safe, and when researchers stopped administering them, sperm production resumed.” Trouble was, when this compound was used in oral form in an experiment, it was ineffective. But head researcher on the study, medicinal chemist, Gunda Georg and her graduate student, Jillian Kyzer haven’t given up. They recently found a breakthrough by tweaking the chemical compounds, swapping out sections for other pieces better suited for oral consumption. Forbes reports the team has discovered a ring-shaped segment they’ve dubbed the pyrrole that’s yielding promising results, but they have yet to reveal exactly what this section entails as patents are still pending.

Despite this awesome new discovery, it may still take a while before we’ll see anything hit the market. But hooray for more options!

Source: Forbes